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Calcium Phosphate Biomaterials – Solubility of Calcium Phosphates

Most calcium phosphates are classified as resorbable biomaterials. This means that under physiological conditions they will dissolve. The benefit of calcium phosphate biomaterials is that the dissolution products can be readily assimilated by the human body.
Calcium Phosphates as Bone Defect Fillers

Due the resorbable nature of calcium phosphate, with the general exception of hydroxyapatite, they have been proposed as potential bone defect fillers. In this application, they would fill the void and gradually dissolve away, being replaced by bone. However, the uncontrollable resorption rate has hindered their uptake in clinical applications.